Preface

Aging is a complex process that is influenced by multiple genetic, environmental, and lifestyle factors. One important biological process during aging is the slow decline of NAD+ levels in our cells.

As we age, our bodies produce less NAD+ from its precursor, NMN. Aging causes more oxidative stress, DNA damage, and inflammation. These factors lead to lower levels of NAD+.This decline affects cellular function and shows visible signs of aging. It also causes NAD+ levels to drop faster than our bodies can replace them.

Scientists have explored various ways to increase NAD+ levels. Researchers have found that only the NAD+ precursor NMN is currently safe and effective in human trials. This is true despite the fact that there are many other strategies available.

What Is NMN?

Nicotinamide mononucleotide (NMN) is a natural compound that plays a vital role in increasing the level of NAD+ (nicotinamide adenine dinucleotide) in the body. NMN has a chemical structure with three parts. These parts are a phosphate group, a ribose sugar, and a nicotinamide base.

What are the effects of lack of NMN?

1. Reduced Cellular Energy Production

NAD+ plays a vital role in the production of energy within your cells. It helps convert food into ATP, your body’s main energy currency. Should you fail to consume sufficient NMN daily, your levels will decrease. This drop can reduce mitochondrial function.

As a result, you may feel tired, low on energy, and sluggish in your daily life. This becomes especially true as you age, leading to decreased physical and mental endurance.

2. Impaired DNA Repair

NAD+ is essential for activating sirtuins, which are important enzymes involved in DNA repair and cell maintenance. However, low NAD+ levels because of insufficient NMN can impair the body's ability to repair damaged DNA. This leads to DNA damage. This damage speeds up aging, increases the risk of cancer, and causes various age-related diseases.

3. Increased Inflammation

Chronic inflammation, also known as inflammaging, plays a major role in age-related diseases. These include heart disease, diabetes, and arthritis. NAD+ regulates inflammation by affecting immune cells and inflammatory markers.

Without enough NAD+ (from NMN), the body struggles to control inflammation. Over time, this can cause chronic inflammation, speed up aging, and raise the risk of disease.

4. Decline in Metabolism

NAD+ is involved in regulating metabolism, including the processing of glucose and fat. If you don't have enough NAD+ in your daily life, your metabolism slows down. This can cause weight gain, insulin resistance, and a higher risk of type 2 diabetes. In addition, a higher incidence of obesity and other metabolic disorders associates with poor metabolic function.

5. Accelerated Aging

Too much energy decline, poor DNA repair, inflammation, mitochondrial problems, and bad metabolism can cause clear signs of aging. These signs include wrinkles, gray hair, less skin elasticity, and reduced brain function. Not only that, the body loses its ability to maintain homeostasis, which leads to both physical and mental aging.

What is nmn supplement？

NMN supplements contain synthetic or naturally derived NMN, formulated to be bioavailable. Usually available in capsule and powder form. The purpose of supplementation is to restore NAD+ levels to provide optimal cellular function.

Effects of NMN supplements：

1. Increase energy levels

It can enhance mitochondrial function by increasing NAD+ levels, which is essential for converting nutrients into energy. This can improve endurance, reduce fatigue, and enhance physical performance.

A study of 48 trained young and middle-aged runners found that those who took NMN daily for six weeks showed better aerobic capacity. Researchers compared this to the control group. The researchers think that the better performance in runners taking NMN may come from improved oxygen use in their muscles.

2. Support DNA repair

NMN can activate sirtuins. These are enzymes that help repair damaged DNA. They also protect cells from aging. This is essential for reducing the risk of diseases associated with genetic damage, such as cancer and neurodegenerative diseases.

3. Promote heart health

By improving blood flow and reducing oxidative stress, NMN supplements help maintain cardiovascular health and support overall longevity.

4. Improve skin health

NMN supports the repair and regeneration of skin cells, enhancing elasticity and reducing the appearance of wrinkles. For many women, skin care is an essential step, and it helps fight oxidative stress, which can play a good skin care effect.

5. Enhance cognitive function

Higher NAD+ levels help protect brain cells. They may slow down cognitive decline and lower the risk of age-related brain diseases like Alzheimer's and Parkinson's. For the elderly, taking related supplements can reduce their risk of acquiring these risks.

6. Regulate metabolism

NMN helps metabolic health by improving how the body regulates glucose. It also boosts fat metabolism. This may help prevent or control metabolic disorders like diabetes and obesity.

A small study involved 25 overweight or obese women with prediabetes. They consumed 250 mg of NMN each day for a span of 10 weeks. The results showed improved insulin signaling and sensitivity in their skeletal muscle. This was better than the results from the placebo group.

Some evidence suggests that IV treatment with NMN may help lower triglyceride levels. Human studies on NMN's effects on blood lipids, blood sugar, and insulin levels are still ongoing.

Is NMN safe? Are there any side effects?

Based on available research and clinical trials, experts generally consider NMN (nicotinamide mononucleotide) supplements to be safe for most people. Many studies, both in animals and humans, have shown that taking NMN at recommended doses does not cause serious side effects.

However, like any supplement, people may respond differently. If you take any medications, talk to your healthcare provider. They can help you decide if new supplements are safe and right for you.

How to Take NMN Supplements for Maximum Benefit？

The first thing to buy is products from brands certified by trusted agencies like the FDA or GMP. This helps ensure the supplement is safe. Secondly, adding other substances to the product will help you absorb and use it better. This will also improve other aspects.

Resveratrol, a compound found in red wine and some plants, works synergistically with NMN by activating NAD+-dependent sirtuins. Combining these two supplements can boost their anti-aging effects. They support DNA repair, energy production, and longevity.

Resveratrol also has mild blood-thinning properties. It could potentially enhance the effectiveness of drugs like aspirin or warfarin.

David Sinclair is a famous anti-aging researcher at Harvard University. He has many years of experience studying resveratrol, NAD+, and sirtuins. He is also running human trials.

He is also incorporating NMN into his lifestyle.. After using it for a while, he is happy to say that his blood lipid profile has improved a lot. He feels full of energy every day. His blood markers at the age of nearly 60 are closer to those of a 31-year-old.

In addition, taking NMN supplements correctly ensures optimal absorption and effectiveness. Typical dosages range from 250 mg to 1,000 mg per day, depending on age, health status, and personal goals. Most people will choose the nmn 18000 product.

Start with a lower dose and adjust as needed. For athletes or those seeking maximum anti-aging benefits, higher doses may be appropriate under medical supervision.

where to buy nmn？

With all that said, maybe you are looking for a reliable source to buy high-quality NMN supplements? A good choice is to buy directly from AIDEVI. This brand dedicates itself to quality, safety, and effective health solutions. AIDEVI NMN products provide optimal bioavailability, ensuring your body absorbs the maximum benefits of NAD+ precursors for anti-aging and vitality.

Why choose AIDEVI for your NMN supplement?

1. High Purity

AIDEVI produces NMN supplements by adhering to the highest quality standards, avoiding unnecessary additives, and conducting purity tests to guarantee a superior product.

2. Clinically Backed

The formula relies on research conducted by Nobel Prize winner Michael Levitt. It combines NMN with other helpful ingredients like resveratrol to improve effectiveness.

3. Certified and Safe

AIDEVI products meet strict quality standards, like FDA and GMP. The brand guarantees their safety and authenticity for your peace of mind.

Safety Tips

Keep in mind that some NMN supplements contain other ingredients, such as PQQ and other additives, that have been shown to have positive effects on aging and other aspects of health.

While NMN has not been shown to interact with medications or be associated with adverse side effects, everyone is different, and other ingredients in NMN supplements may not be safe for you.

 Always consult a healthcare provider to evaluate potential interactions, depending on your medical history and your current medications.

Conclusion

NAD+ is important for making energy in cells, repairing DNA, and regulating metabolism. However, it decreases as we age. This decline can speed up signs of aging, like fatigue, inflammation, and skin aging.

NMN supplements help restore declining NAD+ levels. NMN can boost the concentrations of NAD+. This helps improve mitochondrial function.

It also promotes cardiovascular and dermatological health. Additionally, NMN enhances brain function and helps regulate metabolism. Overall, it provides strong support for anti-aging and vitality.It can be one of the supplements in your life.